Sachin A Gupte Selected Research

6-Aminonicotinamide (6 Aminonicotinamide)

8/2006	Glucose-6-phosphate dehydrogenase-derived NADPH fuels superoxide production in the failing heart.
6/2006	Hypoxia promotes relaxation of bovine coronary arteries through lowering cytosolic NADPH.

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Sachin A Gupte Research Topics

Disease

25	Hypoxia (Hypoxemia) 01/2022 - 04/2002
11	Pulmonary Hypertension 01/2021 - 06/2008
8	Heart Failure 01/2013 - 07/2005
5	Hypertension (High Blood Pressure) 01/2022 - 07/2005
5	Vascular Diseases (Vascular Disease) 01/2022 - 04/2009
4	Glucosephosphate Dehydrogenase Deficiency 01/2022 - 01/2013
4	Hypertrophy 01/2021 - 09/2008
4	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2021 - 01/2018
4	Vascular Remodeling 01/2018 - 02/2015
3	Inflammation (Inflammations) 01/2022 - 01/2022
3	Pulmonary Arterial Hypertension 01/2022 - 12/2014
3	Heart Diseases (Heart Disease) 02/2013 - 06/2007
2	Isolated Systolic Hypertension 01/2018 - 01/2018
2	Right Ventricular Hypertrophy 09/2016 - 12/2014
2	Ventricular Remodeling 12/2014 - 01/2013
2	Cardiovascular Diseases (Cardiovascular Disease) 02/2013 - 09/2008
2	Cardiomyopathies (Cardiomyopathy) 05/2012 - 08/2007
2	Atherosclerosis 09/2008 - 07/2005
1	Hematologic Neoplasms (Hematological Malignancy) 01/2022
1	Acquired Immunodeficiency Syndrome (AIDS) 01/2021
1	Neoplasms (Cancer) 01/2018
1	Obesity 01/2018
1	Left Ventricular Dysfunction 12/2014
1	Diastolic Heart Failure 12/2014
1	Stroke (Strokes) 03/2014

Drug/Important Bio-Agent (IBA)

16	NADP (NADPH)IBA 01/2016 - 04/2002
13	Glucosephosphate Dehydrogenase (Glucose 6 Phosphate Dehydrogenase)IBA 01/2022 - 08/2005
10	Superoxides (Superoxide)IBA 02/2013 - 05/2005
9	Oxidoreductases (Dehydrogenase)IBA 01/2013 - 01/2005
8	EnzymesIBA 01/2022 - 07/2005
8	Glucose (Dextrose)FDA LinkGeneric 01/2018 - 06/2007
7	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2014 - 07/2005
4	Oxygen (Dioxygen)IBA 01/2022 - 08/2005
4	Proteins (Proteins, Gene)FDA Link 01/2020 - 08/2006
4	CalciumIBA 01/2017 - 11/2004
4	Soluble Guanylyl CyclaseIBA 03/2010 - 08/2003
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 03/2010 - 08/2003
4	NADPH Oxidases (NAD(P)H oxidase)IBA 04/2009 - 01/2005
3	CytokinesIBA 01/2022 - 01/2022
3	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 01/2018 - 01/2016
3	AcidsIBA 01/2018 - 11/2004
3	Sulfhydryl Compounds (Thiols)IBA 08/2010 - 06/2006
3	PeroxidesIBA 08/2010 - 12/2003
3	NAD (NADH)IBA 06/2010 - 01/2005
3	Oxidants (Oxidizing Agents)IBA 03/2010 - 05/2005
2	Angiotensin IIIBA 01/2022 - 09/2008
2	Serum Response FactorIBA 01/2022 - 01/2021
2	DioxygenasesIBA 01/2022 - 01/2020
2	myocardinIBA 01/2021 - 02/2015
2	Histones (Histone)IBA 01/2021 - 02/2015
2	AndrosteroneIBA 01/2020 - 06/2006
2	Small Interfering RNA (siRNA)IBA 01/2020 - 06/2010
2	20-hydroxy-5,8,11,14-eicosatetraenoic acidIBA 01/2018 - 01/2018
2	FructoseIBA 01/2013 - 05/2012
2	Heme (Haem)IBA 08/2010 - 03/2010
2	Adenosine Triphosphate (ATP)IBA 06/2010 - 06/2006
2	Pyruvic Acid (Pyruvate)IBA 06/2010 - 06/2006
2	Serotonin (5 Hydroxytryptamine)IBA 06/2010 - 08/2003
2	Vasodilator Agents (Vasodilators)IBA 03/2010 - 08/2005
2	Protein Kinase CIBA 04/2009 - 06/2006
2	6-Aminonicotinamide (6 Aminonicotinamide)IBA 08/2006 - 06/2006
2	cyclopiazonic acidIBA 06/2006 - 11/2004
2	ProstaglandinsIBA 06/2006 - 11/2004
2	Potassium Channels (Potassium Channel)IBA 08/2005 - 11/2004
1	Interleukin-6 (Interleukin 6)IBA 01/2022
1	E2F Transcription FactorsIBA 01/2022
1	DNA (Deoxyribonucleic Acid)IBA 01/2022
1	Lysine (L-Lysine)FDA Link 01/2022
1	MethyltransferasesIBA 01/2022
1	Transcription Factors (Transcription Factor)IBA 01/2022
1	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 01/2021
1	NG-Nitroarginine Methyl Ester (L-NAME)IBA 01/2020
1	Amino Acids FDA Link 01/2020
1	Urea (Carbamide)FDA LinkGeneric 01/2020
1	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2020
1	Protein Isoforms (Isoforms)IBA 01/2020
1	RNA (Ribonucleic Acid)IBA 01/2020
1	Nitric Oxide Synthase (NO Synthase)IBA 01/2020
1	CarbonIBA 01/2018
1	LipidsIBA 01/2018
1	Glutamine (L-Glutamine)FDA Link 01/2018
1	NucleosidesIBA 01/2018
1	ElastinIBA 01/2018
1	Matrix Metalloproteinase 12IBA 01/2018
1	Arachidonic Acid (Vitamin F)IBA 01/2018
1	Hydroxyeicosatetraenoic Acids (HETE)IBA 08/2017
1	von Willebrand FactorIBA 08/2017
1	EicosanoidsIBA 08/2017
1	AldosteroneIBA 09/2016
1	Mixed Function Oxygenases (Monooxygenases)IBA 01/2016
1	IronIBA 01/2016
1	Cyclin AIBA 02/2015
1	NucleotidesIBA 12/2014
1	A 17 (A-17)IBA 12/2014
1	Dehydroepiandrosterone (DHEA)IBA 12/2014
1	Acetyl Coenzyme A (Acetyl-CoA)IBA 12/2014
1	pyridineIBA 12/2014
1	IsoprostanesIBA 03/2014

Therapy/Procedure

1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 01/2020
1	Therapeutics 10/2014